CVE-2025-12921Public exploitNetwork attack vectorHinoki check available

Authenticated file disclosure via external entity resolution

Published Nov 9, 2025 · Updated Nov 9, 2025

External entity injection in OpenClinica Community Edition 3.0 through 3.13 allows remote authenticated users to read local files. The CRF Data Import endpoint passes the uploaded xml_file document to an XML parser that resolves attacker-controlled external entities and returns resolved file content in its UI error block. A Data Manager or Clinical Research Coordinator account is required, and disclosure is limited to files readable by the OpenClinica application user.

CVSS severity4.3
Medium
EPSS probability0.53%
Next 30 days · Sep 16, 2026
Known exploitationUnconfirmed
Based on sourced intelligence
Hinoki checkAvailable
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Summary

What happened

External entity injection in OpenClinica Community Edition 3.0 through 3.13 allows remote authenticated users to read local files. The CRF Data Import endpoint passes the uploaded xml_file document to an XML parser that resolves attacker-controlled external entities and returns resolved file content in its UI error block. A Data Manager or Clinical Research Coordinator account is required, and disclosure is limited to files readable by the OpenClinica application user.

The record

CVE
CVE-2025-12921
Published
Nov 9, 2025
Updated
Nov 9, 2025
Vendor
OpenClinica
Product
OpenClinica Community Edition
Classifications
CWE-74, CWE-91, T1190
Attack vector
network
Privileges
authenticated

Timeline

How it unfolded

  1. Nov 9, 2025CVE publishedPublication date reported by the CVE source.
  2. Nov 9, 2025Record updatedLatest update available in the CVE record.

Exploitability

Present is not the same as exploitable

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Is a vulnerable build present?

Compare these published version ranges with your installed build and any vendor patches.

  1. Affected versionversion=3.0
  2. Affected versionversion=3.1
  3. Affected versionversion=3.10
  4. Affected versionversion=3.11
  5. Affected versionversion=3.12
  6. Affected versionversion=3.12.0
  7. Affected versionversion=3.12.1
  8. Affected versionversion=3.12.2
  9. Affected versionversion=3.13
  10. Affected versionversion=3.2
  11. Affected versionversion=3.3
  12. Affected versionversion=3.4
  13. Affected versionversion=3.5
  14. Affected versionversion=3.6
  15. Affected versionversion=3.7
  16. Affected versionversion=3.8
  17. Affected versionversion=3.9

What conditions does exploitation require?

Attack vectornetwork
Required privilegesauthenticated

What is affected?

OpenClinica · OpenClinica Community Editionversion=3.0; version=3.1; version=3.10; version=3.11; version=3.12; version=3.12.0; version=3.12.1; version=3.12.2; version=3.13; version=3.2; version=3.3; version=3.4; version=3.5; version=3.6; version=3.7; version=3.8; version=3.9

Published CVSS scores

4.3VulDBCVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N
8.8NIST NVDCVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H
2.1VulDBCVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N/E:P
4.0VulDBAV:N/AC:L/Au:S/C:P/I:N/A:N

CVSS describes severity. EPSS estimates exploitation probability.

Attacks

What attackers are doing with it

Daily unique IPs observed by Shadowserver honeypots for known exploited vulnerabilities (KEVs). Missing observations do not establish an absence of attacks.

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No observations available

Sep 10, 2026Sep 16, 2026
Latest reporting daySep 16, 2026
Latest daily unique IPsUnavailable
Prior 30-day averageUnavailable
SourceShadowserver honeypots (KEV)
Vectornetwork
Privilegesauthenticated
Known exploitationUnconfirmed
Public exploitPublished

Weakness, pattern, technique

CWE-74Improper Neutralization of Special Elements in Output Used by a Downstream Component ('Injection')
CWE-91XML Injection (aka Blind XPath Injection)
T1190Exploit Public-Facing Application

Public exploit references

Labels summarize the accepted research assessment. They do not indicate a test against your environment.

Technologies

Your stack

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Your stack

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